Research at Jothydev’s Diabetes Research Centre



Milestones:


  1. First centre to introduce smart insulin pumps in the treatment of diabetes in 2004 in Kerala.
  2. Dr. Jothydev was the first speaker from Kerala at the prestigious American Diabetes Association 2009.
  3. Dr. Jothydev was the first invited speaker from Kerala at the prestigious International Diabetes Federation in 2009.
  4. The first speaker from Kerala at Advanced Technologies and Treatments in Diabetes in 2014.
  5. Sunitha Jothydev was an invited speaker at International Diabetes Federation in 2009, Montreal, Canada.
  6. Dr. Jothydev is the only speaker from Kerala to have delivered academic lectures on diabetes in almost every city in India and in more than 20 countries across the globe.
  7. First in Kerala to have introduced Libre Pro Ambulatory Glucose Profile on 25 March 2015.
  8. First to deploy the first generation artificial pancreas 640G in Kerala on 3rd Sep 2015.

Ms. Gopika Krishnan heads the department of academics and research.
For enquiring on academic courses or to work with us email: gopika@jothydev.net


Select Publications & Presentations

 

107 Vitale RJ, Pillai PB, Krishnan G, Jothydev S, Kesavadev J.The two levels of care for diabetes in a developing country: Mechanisms for improved intermediate health outcomes. Diabetes Metab Syndr. 2015 Oct 8. pii: S1871-4021(15)30013-8.
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106 Intensifying Insulin Therapy in Type 2 Diabetes: Choices & Challenges. J Assoc Physicians India. 2015 May;63(5 Suppl):8-14.
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105 105. CSII as an Alternative Therapeutic Strategy for Managing Type 2 diabetes: Adding the Indian Experience to a Global Perspective. Curr Diabetes Rev. 2015 Dec 7.
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104 Understanding the safety of the new ultra long acting basal insulin. J Assoc Physicians India. 2014 Jan;62(1 Suppl):35-42.
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103 Forum for Injection Technique (FIT), India: The Indian recommendations 2.0, for best practice in Insulin Injection Technique, 2015. Indian J Endocrinol Metab. 2015 May-Jun;19(3):317-31
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102 Periodic follow up with telemanagement system for 15 years and significant reduction in vascular complications in T2DM. Abstracts from ATTD 2016 9th International Conference on Advanced Technologies & Treatments for Diabetes. Milan, Italy–February 3–6, 2016. Diabetes Technology & Therapeutics. February 2016, 18(S1): A-1-A-139.
Read

101 Comparing iPro2 with Libre for Sensor Accuracy and User Friendliness. Abstracts from ATTD 2016 9th International Conference on Advanced Technologies & Treatments for Diabetes. Milan, Italy–February 3–6, 2016. Diabetes Technology & Therapeutics. February 2016, 18(S1): A-1-A-139.
Read

100 ’How significant are wrong injection techniques in a real world diabetes care setting?’ . World Diabetes Congress, IDF, Vancouver, Canada: 30 Nov-4 Dec 2015

99 ‘Cost effective customisation of targets: Outcomes after 12 years of telemedicine in 853 patients with type 2 diabetes’. World Diabetes Congress, IDF, Vancouver, Canada: 30 Nov-4 Dec 2015

98 ‘How proactive is the spouse support in diabetes care?’. World Diabetes Congress, IDF, Vancouver, Canada: 30 Nov-4 Dec 2015

97 Unity in diversity: Religious festivals and its impact on diabetes in India’. World Diabetes Congress, IDF, Vancouver, Canada: 30 Nov-4 Dec 2015

 
96 AACE, Nashville May 2015
Insulin Pumps For Life Vs Insulin Pumps For Luxury-The Indian Experience In Type 2 Diabetes

95 RSSDI 2015
A head to head comparison of two popular CGM devices in India - iPro2 vs. FreeStyle Libre Pro.

94 RSSDI 2015
Normalising vitamin D levels correlates with better glycaemic control: an observational study in a cohort in Kerala.

93 Consensus Evidence-based Guidelines for Use of Insulin Pump Therapy in the Management of Diabetes as per Indian Clinical Practice. Journal of Association of Physicians India, July 2014.
Read

92 Telemedicine for Diabetes Care: An Indian Perspective: feasibility and efficacy. Indian J Endocrinol Metab. Nov 2015
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91 Effect of Sitagliptin on Cardiovascular Outcomes in Type 2 diabetes. N Eng J Med. Jul 2015
Read more

90 Fasting in Ramadan with an Insulin Pump. J Pak Med Assoc. May 2015
Read

89 Intensifying Insulin Therapy in Type 2 Diabetes: Choices & Challenges. J Assoc Physicians India. 2015
Read

88 Challenges in Type 1 diabetes management in South East Asia: Descriptive Situational Assessment. Indian J Endocrinol Metab. Sep-Oct 2014.
Pubmed link
Journal link

87 Consensus guidelines for glycemic monitoring in type 1/type 2 & GDM. Diabetes & Metabolic Syndrome: Clinical Research & Reviews. May 2014.
Pubmed link

86 Efficacy and safety of liraglutide therapy in 195 Indian patients with type 2 diabetes in real world setting. Diabetes & Metabolic Syndrome: Clinical Research & Reviews. May 2014.
Read

85 Consensus Evidence-based Guidelines for Use of Insulin Pump Therapy in the Management of Diabetes as per Indian Clinical Practice. J Assoc Physicians India. Jul 2014.

84 Clinical experience with insulin detemir, biphasic insulin aspart and insulin aspart in people with type 2 diabetes: Results from the Trivandrum cohort of the A1chieve study. Indian J Endocrinol Metab. Nov 2013

83 Improvement of glycemic control with addition of insulin detemir to existing antidiabetic therapy: a sub-group analysis of A1chieve observational study. J Assoc Physicians India. Jan 2013.

82 American Diabetes Association, Boston, 2015 :
Utilization of Biosimilar insulin in Asian patients with diabetes – The Joint Asia Diabetes Evaluation (JADE) program. Diabetes. 2015; June 64 (suppl 1).

81

American Diabetes Association, Boston, 2015 :
Exploring and resolving the impact of food on post prandial glycemic excursions in a rice-eating population in S.India. Diabetes. 2015; June 64 (suppl 1).
Read


80 American Diabetes Association, Boston, 2015 :
Periodic CGM in T2DM: exploring benefits across various therapy choices. Diabetes. 2015; June 64 (suppl 1).
Read

79 American Diabetes Association, Boston, 2015 :
Insulin-sparing effect of and Severe Hypoglycemia with Sitagliptin vs. Glimepiride. Diabetes. 2015;June 64 (suppl 1).
Read

78 American Diabetes Association, Boston, 2015 :
Comparing two models of diabetes care comprehensive education and telemonitoring vs. limited care. Diabetes. 2015; June 64 (suppl 1).
Read

77 Advanced Technologies & Treatments for Diabetes 8th International Conference 2015
Role of Home Blood Pressure Monitoring in Halting the Progression of Diabetic Kidney Disease: 6 Year Follow up Data.
Read

76 Advanced Technologies & Treatments for Diabetes 8th International Conference 2015
Impact of Insulin Pump Therapy on Erectile Dysfunction in Type 2 Diabetes.
Read

75 European Association for the Study of Diabetes (EASD), Vienna, Austria 2014
Prevalence of undetected thyroid disorders in subjects with diabetes in South India: a cohort analysis
Read1 | Read2

74 Continuous Glucose Monitoring in 432 T2D Patients for Assessment of Safety and Cost effectiveness in Reaching A1C Targets. American Diabetes Association 2014.
Link to abstract
Abstract ePaper
Read

73 Various Emerging Techniques in Insulin Delivery Systems. Innovative Approaches in Type 2 diabetes. Chapter 42. Page 398-408. Published by Micro labs Ltd.

72 Very Low Protein Diet with Ketoanalogue Supplementation in Diabetic Keidney Disease: Case Studies. Dietary Protein Restriction in Chronic Kidney Disease. Page 35-44 Published by Elsevier India Pvt.Ld.

71 Insulin Pump in Type 2 diabetes mellitus. Jaypee Brothers Medical Publishers (P) Ltd.Page 120-133 World Clinics Diabetology Type 2 diabetes mellitus.World Clin Diabetol.2014;1(1):120-33

70 The young Indian female with type 1 diabetes: challenges with marriage.
OP-0294 Oral Presentation. International Diabetes Federation (IDF) World Diabetes Congress Dec 2013

69 Safety of pneumococcal and influenza vaccination in diabetes patients in South India. International Diabetes Federation (IDF) World Diabetes Congress Dec 2013

68 Continuous customized education via telemedicine: outcome data of events over 8 years. International Diabetes Federation (IDF) World Diabetes Congress Dec 2013

67 High prevalence of undetected elevated blood pressure in Kerala population: Diabscreen Kerala 22. International Diabetes Federation (IDF) World Diabetes Congress Dec 2013

66 Use of Insulin Pumps in T2DM in India: Merits and Demerits learnt over a decade. Invited Speaker. Advanced Technologies and Treatments for Diabetes (ATTD), Vienna, Austria 2014
Read

65 ‘CLINICAL UTILITY OF CGM IN PRE-DIABETES AND ITS IMPACT ON MODIFYING LIFESTYLES’ Advanced Technologies and Treatments for Diabetes (ATTD),
Vienna, Austria 2014
Read

64 ‘LIVE BRIEF WEEKLY EDUCATIONAL QUESTIONNAIRE VIA DTMS® AS A TOOL TO IMPROVE THE ACCEPTABILITY AND OUTCOME IN TYPE 2 DIABETES.’ Advanced Technologies and Treatments for Diabetes (ATTD), Vienna, Austria 2014
Read

63 C-peptide levels not affected by duration of diabetes in a telemedicine based long-term follow up programme. European Association for the Study of Diabetes (EASD), Barcelona 2013. <
Read

62 Barriers and solutions to diabetes management: An Indian perspective. Indian J Endocrinol Metab. 2013 Jul;17(4):594-601.
Read

61 Low requirements for average statins dosage in South Indian populations titrated to target lipid parameters. European Association for the Study of Diabetes (EASD), October 1-5, 2012.
Read 1 | Read 2

60 Time of Insulin Initiation, Duration of disease and onset of Erectile Dysfunction in Indian men with T2D. 73d Scientific Sessions, American Diabetes Association, Chicago, Illinois, 2013.
Read1 | Read2

59 Long Term Impact of Initial Insulin Therapy in New Onset T2D: 5 year Retrospective Data. 73d Scientific Sessions, American Diabetes Association, Chicago, Illinois, 2013.
Read | Read2| Read3

58 Superiority of a Telemedicine Based Counselling in Ensuring Multi Drug Compliance in T2D. 698-P, 73d Scientific Sessions, American Diabetes Association, Chicago, Illinois, 2013
Read 1 | Read 2

57 Normal Vitamin D Levels Correlates with Lower HbA1c: A Cross Sectional Study Among 1270 Type 2 Diabetes Patients in South India. 73d Scientific Sessions, American Diabetes Association, Chicago, Illinois, 2013
Read

.56 Once-daily initiation of basal insulin as add-on to metformin: a 26-week, randomized, treat-to-target trial comparing insulin detemir with insulin glargine in patients with type 2 diabetes. Diabetes Obes Metab.2013 Feb 19.
a. Pubmed

55 Attitudes and Behaviour Of Type 2 Diabetes Patients on Insulin Pumps. Diabetes Technology & Therapeutics. February 2013, 15(S1): A-43
a. Journal
b. PDF
c. Conference

54 Glycemic Variability in Type 2 Diabetes Correlates with Total Daily Dose of Insulin And Use of Sulfonlyureas. Diabetes Technology & Therapeutics. February 2013, 15(S1): A-66
a. Journal
b. PDF
c. Conference

53 Suggested Use Of Vaccines In Diabetes. Indian Journal of Endocrinology and Metabolism. Vol 16 Issue 6 Nov-Dec 2012
a. Journal
b. Pubmed
c. PDF link

52. Kesavadev J, Shankar A, Pillai PBS, Krishnan G, Jothydev S. Cost-Effective Use of Telemedicine and Self-Monitoring of Blood Glucose via Diabetes Tele Management System (DTMS) to Achieve Target Glycosylated Hemoglobin Values Without Serious Symptomatic Hypoglycemia in 1,000 Subjects with Type 2 Diabetes Mellitus-A Retrospective Study. Diabetes Technol. Ther. 2012 Sep;14(9):772–776.[cited 2012 Sep 24 ]
a. Pubmed link
b. Journal link

51. Liraglutide Therapy beyond Glycemic Control: an Observational Study in Indian Patients with Type 2 Diabetes in Real World Setting. International Journal of General Medicine, April 2012 Volume 2012:5 Pages 317 – 322
a. Pubmed link
b. Free PMC Article
b. PDF link
c. Full text link
d. video link

50. "An Asian Indian woman with Wolfram syndrome on Insulin pump: successful pregnancy and beyond" Kesavadev.J et al. Diabetes Technology and Therapeutics, Vol. 13, no. 7, July 2011.
a. Pubmed
b. Full text link

49. Continuous Insulin Infusion Systems in Type 2 Diabetes, Vol. 59, Apr 2011.
a.Pubmed
b.JAPI link

48. The usage of basal-plus regimen in the management of diabetes, Indian Journal of Clinical Practice (IJCP) .
a. PDF link

47. “Use of Insulin Pumps in India: Suggested Guidelines based on Experience and Cultural Differences”, Diabetes Technology & Therapeutics, October, 2010.
a. Pubmed
b. Free full text : Journal link

46. “Reduction of glycosylated hemoglobin following 6 months of continuous subcutaneous insulin infusion in an Indian population with type 2 diabetes”, Diabetes Technology and Therapeutics, August, 2009.
b. Pubmed
c. Free full text : Journal link

45. "A1c, BP and LDL Goals— Successful Use of Telemedicine (DTMS®) in 1000 Compliant T2DM Subjects over 6 Months"-229- OR, Diabetes, July supplement, American Diabetes Association, San Diego, California, 2011
a. Webcast
b. Abstract

44. “Significance of Screening for Thyroid Disorders in Type 2 Diabetes-” 1377-P, Diabetes, July supplement, American Diabetes Association, San Diego, California, 2011
Abstract

43. “Utility of CGM over Conventional SMBG in Making Treatment Changes in Insulin Requiring T2DM Patients”- 912 P Diabetes, July supplement, American Diabetes Association, San Diego, California, 2011
Abstract

42. “Change in Antihypertensive Medication Dose Following Initiation of Liraglutide in Patients”- 2357-PO, Diabetes, June supplement, American Diabetes Association, San Diego, California, 2011
Abstract

41. Tele-medicine via DTMS® is cost-effective and satisfactory: still why it fails in minority with T2DM? O-0427. International Diabetes Federation, World Diabetes Congress, December 2011
a. Webcast
b. Abstract

40. Acceptability of a home delivered assessment of lab & vital signs in Diabetes mellitus & its role in treatment motivation P-1798. International Diabetes Federation, World Diabetes Congress, December 2011
Abstract

39. Effectiveness of Liraglutide in Routine Clinical Practice: Six Months Follow-Up Data from India P-1852.International Diabetes Federation, World Diabetes Congress, December 2011
Abstract

38.

High Bed Time Glucose and Early Morning Low Sugars in Elderly Subjects with Type 2 Diabetes (T2DM): An Incidental Finding with Clinical Significance.
881-P. American Diabetes Association, Philadelphia, Pennsylvania 2012


37. Patterns of Glycemic variability(GV) in Indian Type 2 diabetes(T2DM) patients on Insulin and Oral Hypoglycemic Agents(OHAs) and its Correlation with A1c and Hypoglycemia.
2343-PO.American Diabetes Association, Philadelphia, Pennsylvania 2012

36. Efficacy and Safety of Liraglutide in 195 Patients with Type 2 Diabetes in India: A Retrospective Analysis 2403-PO.American Diabetes Association, Philadelphia, Pennsylvania 2012

35. ATTD 2012 Barcelona
Acceptance of Continuous Glucose Monitoring(CGM) as a Routine Investigation in Diabetes Advanced Technologies and Treatment for Diabetes (ATTD), Barcelona, Spain, 2012
Abstract | Read

34. ATTD 2012 Barcelona
Geographical location and effectiveness of a simple telemedicine program (DTMS®) in diabetes Advanced Technologies and Treatment for Diabetes (ATTD), Barcelona, Spain, 2012
Abstract | Read

33. "Telefollow up and SMBG Via “DTMS”- A Cost Effective Tool for A1c Lowering "– 2083-PO, Diabetes , June supplement, American Diabetes Association, Orlando, 2010 (journal).

32. "High Prevalence of Elevated Transaminases among T2DM in S.India "– 2340-PO, Diabetes , June supplement, American Diabetes Association, Orlando, 2010 (journal).

31. “Significant Alleviation of Neuropathic Pain with Insulin Pumps (CSII) in T2DM subjects previously on MDI”-  Advanced Technologies and Treatment for Diabetes, Basel, Switzerland, 2010.

30. “A Clinician’s Perspective on Liraglutide in Clinical Practice”. Supplement to Journal of Association of Physicians India (JAPI),Vol.58,: 29-30 June 2010 (journal).

29. “Effectiveness and Tolerability of Once Daily Human GLP-1 Analogue Liraglutide in Patients with Type 2 Diabetes in A Real Life Clinical Practice Setting”- PO, ESICON, 2010.

28. ATTD 2011
Advanced Technologies and Treatment for Diabetes (ATTD), London, UK, 2011

a. CGM as a tool For Therapeutic Decision Making (TDM) In Type 2 Diabetes Mellitus P-108

b. Pregnancy, Wolfram Syndrome and Insulin Pump: benefits beyond glycemic controlP-109
Read

27. “Insulins in Continuous Subcutaneous Insulin Infusion”, Asian Journal of Diabetology, April-June 2010

26. “Newer Insulin and Insulin pumps", The Journal of the Association of Physicians of India (Tamil Nadu Chapter)(TAPIJ), May-Aug 2010

25. “Insulin Pumps in India: the success story: untold”- Invited speaker: Dr.Jothydev Kesavadev, RSSDI, Cochin, 2010.

24. “Cost effectiveness of a telefollow up program for diabetes across 5 years” –PO, RSSDI, Cochin, 2010.

23. “Literate Kerala population and reluctance to continue Statins: DIABSCREEN KERALA”, 15- PO, RSSDI, Cochin, 2010.

22. “Refractory Neuropathic Pain and Erectile Dysfunction – Is CSII a Viable ?”- PO, RSSDI, Cochin, 2010.

21. "Cost-Effectiveness of Education Via "DTMSTM" and Achievement of Goals: Evidence Over a Decade", Oral Presentation- Speaker: Dr.Jothydev Kesavadev, American Diabetes Association, Diabetes Education Council Meeting, Orlando, June , 2010.

20. "Advanced Pump Training in Type 2 Diabetes: Pros & Cons", Oral Presentation, Speaker: Gopika Krishnan, American Diabetes Association,   Diabetes Education Council Meeting, Orlando, June, 2010

19. " Role of Continuous Glucose Monitoring in Modifying Diet and Lifestyles in Diabetes subjects "– 268-OR, Oral Presentation, Speaker: Dr.Jothydev Kesavadev, Diabetes, June supplement , American Diabetes Association, New Orleans, USA, 2009 (journal).

18. "Requirement of High Dosage of Insulin in Previous Users of Glibenclamide with Uncontrolled Diabetes" – 2079-PO, Diabetes , June supplement, American Diabetes Association, New Orleans, USA, 2009 (journal).

17. " Indian Patients with Diabetes Experienced Better Glycemic Control, Less Weight Gain and Hypoglycaemia with Insulin Detemir When Switched from NPH and Insulin Glargine in PREDICTIVE™ Study ", Diabetes , June supplement, American Diabetes Association, New Orleans, USA, 2009 (journal).

16. "Good Nutrition: Avoidance of excess weight with Pumps"-  Invited Speaker: Dr.Jothydev Kesavadev, World Diabetes Congress, International Diabetes Federation, Montreal, Canada , October, 2009.

15. "Diabetes and Discrimination: Home and Siblings,"- Invited Speaker: Sunitha Jothydev, World Diabetes Congress, International Diabetes Federation, Montreal, Canada , October, 2009.

14. " Low compliance of Statins in Kerala Rural Population (Diabscreen 14)" -PO, World Diabetes Congress, International Diabetes Federation, Montreal, Canada , October, 2009.

13. " Successful outcome of a multidisciplinary team over an individual approach in imparting diabetes education-”PO, World Diabetes Congress, International Diabetes Federation, Montreal, Canada ,October, 2009.

12. " Reasons for non compliance to Diabetes Tele Medicine Based Follow up Program in Type 2 Diabetes", Advanced Technologies and Treatment for Diabetes, Greece, 2009.

11. "Insulin Pump in 56 Type 2 diabetes subjects: Improvement of sexual satisfaction and neuropathic symptoms" Advanced Technologies and Treatment for Diabetes, Greece, 2009.

10. " Experiences with Insulin Pump in 52 Patients with Type 2 Diabetes in India"- 2021-PO, Diabetes, June Supplement, American Diabetes Association, San Francisco, USA, 2008 (journal).

9. "Insulin Aspart Induced Lipoatrophy in a Patient on Insulin Pump"-2021-PO, Diabetes, June Supplement, American Diabetes Association, San Francisco, USA, 2008 (journal).

8. " High Prevalence of Dyslipidemia and Hypertension Detected in a Screening Program for Diabetes in a Rural population of a Southern State in India, Kerala (DIABSCREEN KERALA-04) "– 2424-PO, Diabetes, June Supplement, American Diabetes Association, San Francisco, USA, 2008 (journal).

7. "A Study on the Effects of Acarbose in Reducing Post-Prandial Blood Glucose and Achieving HbA1c "– 438-P, Diabetes, June Supplement, American Diabetes Association, San Francisco, USA, 2008 (journal).

6. "Reasons for Failure in Achieving Glycemic Targets in a Subset of Indian Patients with Type 2 Diabetes Mellitus in a Telemedicine-Based Follow Up Program", Endocrine Society, San Francisco, USA, 2008.

5. "Achieving Desirable Glycemic Targets without the risks of Hypoglycemia using a Tele
titration program" -0421-P, Diabetes, June Supplement, American Diabetes Association, Chicago, 2007 (journal).


4. "Dramatic Response of Painful Peripheral Neuropathy with Insulin Pump in Type 2
Diabetes" -2097-PO, Diabetes, June Supplement, American Diabetes Association, Chicago, 2007 (journal).


3. ." Use of Acarbose in graded doses in T2 diabetes subjects to achieve postprandial sugars below 140mg/dl and A1c below 6% with a tele medicine based titration program", Indian Medical Gazette, November, 2008.

2. ." Gatifloxacin induced abnormalities in glucose homeostasis in a patient on Glimepiride", Journal of Association of Physicians of India (JAPI), December, 2006 (journal). JAPI link

1. " Diabetes in old age: an emerging epidemic", Journal of Association of Physicians of India (JAPI), November, 2003 (pubmed).

JAPI link

 
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